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video 1

video 2

video 3


Please start by reviewing the notes for Chapter 6 (points 7 through 9 will play an important part in your response). Then, review Videos 1, 2, and 3 (each runs less than five minutes). 

Consider the following dilemma involving a stage 4 cancer patient giving her informed consent to participate in a Phase 1 clinical trial. The patient has exhausted all standard treatment options (like Norma Forey in Video 2), and the only hope for recovery appears to lie in participation in a  Phase 1 clinical trial for an experimental therapy. However, a Phase 1 clinical trial, as we see in Video 1 and in the course notes for Chapter 6, does not offer a reasonable expectation of therapeutic benefit (since the chief objective of a Phase 1 clinical trial is to test the safety of a new drug or treatment). So, a question arises: can a patient suffering from stage 4 cancer give genuine informed consent to participate in a Phase 1 clinical trial if her primary motivation is to receive therapeutic benefit rather than simply to help future cancer patients? Provide a 200 to 300 word response to this question in the text box. Be sure to discuss the elements of genuine informed consent and the concept of therapeutic benefit in your response. You can reference/cite material found in the videos by simply using ‘(Video 1)’, ‘(Video 2),’ etc.

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