Researchers hypothesized that Dengue fever infection is associated with an increased risk of miscarriage.

Researchers hypothesized that Dengue fever infection is associated with an increased risk of miscarriage. At a hospital in South America, 300 women who have experienced a miscarriage in the last two years were identified. 300 women who had a viable pregnancy at the same hospital during the same time frame were identified as controls. Cases and controls were questioned about recent febrile illness and serum was collected and tested for Dengue fever IgM antibodies. Of the 300 women who experienced miscarriages, 150 had a recent diagnosis of Dengue fever (febrile illness and positive Dengue fever IgM antibody test). Of the 300 women who did not experience a miscarriage (delivered their babies at full term), 50 had a recent diagnosis of Dengue fever a. Construct a 2 x 2 table that appropriately shows the cases and controls by exposure status.

b. Calculate the odds ratio and interpret.

describe one advantage to using patients from the same hospital as controls rather than population-based controls.

Describe one strength and one weakness of using the case control study design. Annotations