Colorectal cancer (CRC)
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Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In Saudi Arabia, CRC is the most
commonly diagnosed cancer among Saudi males and ranks third in females with up to 73% of
cases diagnosed at late stage. In this assignment, you are asked to design a genetic association
study to identify CRC susceptibility variants in Saudi population.
You need to provide a written report of 1500 to 2500 words covering the following topics:
– Background
– Genetic basis of the disorder
– Disease phenotype
– Inclusion and exclusion criteria of cases and controls
– Cases and controls proposed demographic data
– Analytical requirements (sample type, technique,.. etc)
– Expected future and subsequent analysis
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